English name: Laboratory for Chemical Analysis
Thesaurus terms (4) : Endocrine disruption; Food poisoning; Pesticides; Pollutant detection
Geographical terms (2) : ANE, North Sea [Marine Regions]; Belgium, Zeeschelde [Marine Regions]
Address:
Salisburylaan 133
9820 Merelbeke
Belgium
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Tel.: +32-(0)9-264 74 51
Fax: +32-(0)9-264 77 82
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Type: Scientific
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| Abstract: |
The laboratory of Chemical Analysis (LCA) of Ghent University was founded in 1992. LCA belongs to the department of Veterinary Public Health and Food Safety and has over 40 years of experience in the detection of residues and contaminants in matrices of animal origin (BELAC accredited under ISO 17025). Based on this elaborate experience, LCA aims to use the most recent, accurate and sensitive analytical methodology to detect, quantify or identify known and unknown residues, contaminants including micropollutants or food components as well as derivatives or metabolites hereof, within a variety of matrices of animal (or vegetable) origin to ensure food safety and quality. This vision is also reflected in the current and future ongoing research projects.
Part of the scientific research performed by LCA is related to the marine or estuarine environment:
- Analysis of micropollutants in the Belgian coastal zone;
- Food safety of seafood;
- The determination of endocrine disruption in the Scheldt Estuary;
- Metabolism and transfer of marine algal toxins to molluscs and the environment.
In the future, the group will continue to develop methods for multi-residue and multi-contaminant analysis of water and biota monsters, using high-resolution mass spectrometry (MS). This analysis will include emerging pollutants such as pharmaceuticals, phthalates, PFCs, phenols, hormones, antibiotics, etc. LCA will also elaborate on the analytical aspects associated with research on marine toxins. The metabolomics-approach, which is already used in several other research areas within the lab, will also serve as a basis for innovative research.
Taking into account the low concentrations of the components to be analysed (ppt or ppb) and the complexity of the matrices, high-tech equipment is required. For this purpose, the laboratory uses 1 LC-MSn and 1 U-HPLC-QqQ-MS/MS which enable the identification and quantification of components and their residues and/or metabolites in complex matrices. Besides that, LCA also has 3 high-resolution apparatus: 1 U-HPLC-Orbitrap-MS, 1 U-HPLC-(Q)-Orbitrap-MS and 1 REIMS-Q-ToF, which allow for multi-component screening, biomarker and metabolome studies. Furthermore, LCA participates in several national projects and collaborates intensively with the laboratory of Environmental Toxicology and Aquatic Ecology (Ugent) and the Operational Directorate Natural Environment of the Royal Belgian Institute of Natural Sciences (RBINS). |
| Publications (15) |
Top | Projects | Datasets |
( 6 peer reviewed ) split up filter
 Ghekiere, A.; Verdonck, F.; Claessens, M.; Monteyne, E.; Roose, P.; Wille, K.; Goffin, A.; Rappé, K.; Janssen, C.R. (2013). Monitoring micropollutants in marine waters, can quality standards be met? Mar. Pollut. Bull. 69(1-2): 243-250. https://dx.doi.org/10.1016/j.marpolbul.2012.12.024, more- Wille, K.; Vanden Bussche, J.; Noppe, H.; De Wulf, E.; Van Caeter, P.; Janssen, C.R.; De Brabander, H.F.; Vanhaecke, L. (2010). A validated analytical method for the determination of perfluorinated compounds in surface-, sea- and sewagewater using liquid chromatography coupled to time-of-flight mass spectrometry. J. Chromatogr. 1217(43): 6616-6622. dx.doi.org/10.1016/j.chroma.2010.03.054, more
- Noppe, H.; Ghekiere, A.; Verslycke, T.; De Wulf, E.; Verheyden, K.; Monteyne, E.; Polfliet, K.; van Caeter, P.; Janssen, C.R.; De Brabander, H.F. (2007). Distribution and ecotoxicity of chlorotriazines in the Scheldt Estuary (B-Nl). Environ. Pollut. 147(3): 668-676. http://dx.doi.org/10.1016/j.envpol.2006.09.016, more
- Noppe, H.; Verslycke, T.; De Wulf, E.; Verheyden, K.; Monteyne, E.; van Caeter, P.; Janssen, C.R.; De Brabander, H.F. (2007). Occurrence of estrogens in the Scheldt estuary: a 2-year survey. Ecotoxicol. Environ. Saf. 66(1): 1-8. https://dx.doi.org/10.1016/j.ecoenv.2006.04.005, more
- Noppe, H.; De Wasch, K.; Poelmans, S.; Van Hoof, N.; Verslycke, T.; Janssen, C.R.; De Brabander, H. (2005). Development and validation of an analytical method for detection of estrogens in water. Anal. Bioanal. Chem. 382(1): 91-98. dx.doi.org/10.1007/s00216-005-3174-8, more
- Du Laing, G.; Bogaert, N.; Tack, F.M.G.; Verloo, M.G.; Hendrickx, F. (2002). Heavy metal contents (Cd, Cu, Zn) in spiders (Pirata piraticus) living in intertidal sediments of the river Scheldt estuary (Belgium) as affected by substrate characteristics. Sci. Total Environ. 289(1-3): 71-81. http://dx.doi.org/10.1016/S0048-9697(01)01025-7, more
- Wille, K.; Noppe, H.; Verheyden, K.; Vanden Bussche, J.; Vanhaecke, L.; De Wulf, E.; Van Caeter, P.; Janssen, C.R.; De Brabander, H.F. (2009). Determination of pharmaceuticals in water samples of the Belgian coastal zone and the Scheldt Estuary using LC-MS, in: Mees, J. et al. (Ed.) VLIZ Young Scientists' Day, Brugge, Belgium 6 March 2009: book of abstracts. VLIZ Special Publication, 41: pp. 78, more
- Claessens, M.; Rappé, K.; Monteyne, E.; Wille, K.; Noppe, H.; Vincx, M.; De Brabander, H.; Roose, P.; Mees, J.; Janssen, C. (2008). INRAM - Integrated Risk Assessment and Monitoring of micropollutants in the Belgian coastal zone, in: Mees, J. et al. (Ed.) VLIZ Young Scientists' Day, Brugge, Belgium, 29 February 2008: book of abstracts. VLIZ Special Publication, 40: pp. 37, more
- Claessens, M.; Rappé, K.; Monteyne, E.; Wille, K.; Noppe, H.; Vincx, M.; De Brabander, H.; Roose, P.; Mees, J.; Janssen, C. (2008). INRAM - Integrated Risk Assessment and Monitoring of micropollutants in the Belgian coastal zone. Universiteit Gent: Gent. 1 poster pp., more
- Janssen, C.R.; Ghekiere, A.; Verslycke, T.; Vincx, M.; Fockedey, N.; Rappé, K.; De Brabander, H.; Noppe, H.; Roose, P.; Monteyne, E.; Vethaak, D.; Mees, J.; Deneudt, K. (2007). Endocrine disruption in the Scheldt estuary distribution, exposure and effects (ENDIS-RISKS). Final report. Belgian Science Policy: Brussels. 106 pp., more
- Noppe, H. (2007). Occurrence of hormones in the Scheldt estuary: an analytical challenge!, in: Mees, J. et al. (Ed.) VLIZ Young Scientists' Day, Brugge, Belgium 2 March 2007: book of abstracts. VLIZ Special Publication, 39: pp. 14, more
- Rappé, K.; Ghekiere, A.; Noppe, H.; Monteyne, E.; Fockedey, N.; Janssen, C.; De Brabander, H.; Roose, P.; Vincx, M. (2007). ENDIS-RISKS: endocrine disruption in the Scheldt estuary - a field study, in: Mees, J. et al. (Ed.) VLIZ Young Scientists' Day, Brugge, Belgium 2 March 2007: book of abstracts. VLIZ Special Publication, 39: pp. 53, more
- Noppe, H.; Verslycke, T.; De Wulf, E.; Verheyden, K.; Monteyne, E.; van Caeter, P.; Janssen, C.R.; De Brabander, H.F. (2006). Occurrence of estrogens in the Scheldt estuary: a 2-year survey, in: Noppe, H. Analytiek van hormoon verstorende stoffen in milieumatrices = Analytics of endocrine disrupting chemicals in environmental matrices. pp. 41-60, more
- Noppe, H.; De Wasch, K.; Poelmans, S.; Van Hoof, N.; Verslycke, T.; Janssen, C.R.; De Brabander, H. (2006). Development and validation of an analytical method for detection of estrogens in water, in: Noppe, H. Analytiek van hormoon verstorende stoffen in milieumatrices = Analytics of endocrine disrupting chemicals in environmental matrices. pp. 21-41, more
- Noppe, H.; Poelmans, S.; Van Hoof, N.; Verslycke, T.; Janssen, C.R.; De Brabander, H. (2005). Endocriene verstoringen in het Schelde estuarium (1) = Endocrine disruptors in the Scheldt estuary (1), in: Mees, J. et al. (Ed.) VLIZ Young Scientists' Day, Brugge, Belgium 25 February 2005: book of abstracts. VLIZ Special Publication, 20: pp. 50, more
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| Projects (2) |
Top | Publications | Datasets |
- ENDIS-RISKS: Endocrine disruption in the Scheldt Estuary: distribution, exposure and effects, more
- INRAM: Integrated Risk Assessment and Monitoring of micropollutants in the Belgian coastal zone, more
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| Datasets (2) |
Top | Publications | Projects |
- Chemical analysis of estrogens, organochlorine and organonitrogen pesticides as possible endocrine disruptors Scheldt-estuary, more
- INRAM concentrations of pharmaceuticals, diruon, isoproturon and endocrine disruptors in the Scheldt estuary, Belgian coastal harbours and Belgian coastal waters, more
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